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Friability is an important factor in tablet formulation to ensure that the tablet can stay intact and withhold its form from any outside force of pressure:
%friability=100 \times \dfrac{(W_o - W_f)}{W_o}
where Wo is the original weight of the tablets, and Wf is the final weight of the tablets after the collection is put through the friabilator. The thickness is determined by the amount of tablet material and the position of the punches in relation to each other during compression.
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